Unable to start debugging on the web server. the project is not configured to be debugged

I lost my mind by searching a solution for this since I need to work on VS 2003/2005/2010 web solution, End up with above error many times and it has wasted my precious time. I do not want the same happening to anyone.

Please give the priority that is marked with High

Solution 1 [High] : Go to Inet Manager select the web site that’s created for the application, in the property select the tab ASP.NET and choose the ASP.NET version then click Ok and the most importantly you will have to do the same exercise for Default Web Site (Select the Default web site -> Property -> Select ASP.NET tab -> Choose ASP.NET version), Both should have same version.

I guess the above solution will work for many

Solution 2 [Medium]: IIS should be configured to use in Integrated Windows Authentication ( Inet manager -> Select the web site created for the application -> Properties -> Select the Directory Security Tab -> Under the Anonymous access and Authentication Control click EDIT -> make sure that check box is ticked for Integrated Windows Authentication.

There are other solutions for the above error I will post it depends on your feedback